CLINICAL PRACTICE Inhalation anaesthetics and climate change†
نویسندگان
چکیده
M. P. Sulbaek Andersen 1*, S. P. Sander 1, O. J. Nielsen 2, D. S. Wagner 3, T. J. Sanford Jr4 and T. J. Wallington 5 1 Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Mail Stop 183-901, Pasadena, CA 91109, USA 2 Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen, Denmark 3 Department of Clinical Sciences, College of Pharmacy, University of Michigan, 428 Church Street, Ann Arbor, MI 48109-1065, USA 4 Department of Anesthesiology, University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5048, USA 5 System Analytics and Environmental Sciences Department, Ford Motor Company, Mail Drop RIC-2122, Dearborn, MI 48121-2053, USA
منابع مشابه
Climate effect of inhaled anaesthetics.
Almost all areas of human activity have the potential to influence climate. The administration of inhalation anaesthetics is one such activity. However, since the first dedicated study in 1989 of the possible role of halogenated anaesthetics, they have received only sporadic interest. Two recent papers, published in this issue of the British Journal of Anaesthesia and in Anesthesia and Analgesi...
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We have shown previously that inhalation anaesthetics inhibit dopamine transport in rat synaptosomes. In order to determine if this inhibition is associated with occupancy of the cocaine site, we examined binding of [3H] (2 beta-carbomethoxy-3 beta-(4-fluorophenyl)-tropane) (3H-CFT) in the presence of halothane or isoflurane 0.01-5 mmol litre-1 in rat brain synaptosomes. Both anaesthetics inhib...
متن کاملComparison of halothane and enflurane anaesthesia for otolaryngological surgery in children.
Halothane and enflurane were compared in 131 children undergoing adenoidectomy with or without tonsillectomy. Anaesthesia for adenoidectomy was induced with thiopentone or Althesin and for tonsillectomy with thiopentone. The response to surgery was minimal (0-5%) during both inhalation anaesthetics. During immediate recovery, respiratory depression was more profound after enflurane than after h...
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To determine the effect of inhalation anaesthetics on the plasma concentration of laudanosine necessary to produce CNS excitation, we administered laudanosine 0.5 mg kg-1 min-1 i.v. to 40 rabbits under eight study conditions: 1.0 or 0.7% halothane, 1.6% isoflurane, 2.0% enflurane, during normocapnia and hypocapnia; 70% nitrous oxide, alone and with 1.0% halothane, and room air (control). At the...
متن کاملThe technique of inhalation anaethesia in experimental investigation in the rat.
The rat is the most frequently used animal in scientific inquiry conducted for the purpose of advancing basic knowledge that may lead to an improvement in the results of treatment. Understanding of the pharmacological properties of inhalation anaesthetics, in combination with monitoring of their concentration in the inspired and end-tidal gas, together provide safe and precise control of the de...
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